Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration.

"... microneedles ..., recently, have been used to promote wound healing ... and the results are promising."

"... for external tissue regeneration, it is easy to use without need of professional operation like hypodermic injection."

Videnskabelig reference

Lyu, S., Dong, Z., Xu, X., Bei, H. P., Yuen, H. Y., James Cheung, C. W., Wong, M. S., He, Y., & Zhao, X. (2023). Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration. Bioactive materials, 27, 303–326. https://doi.org/10.1016/j.bioactmat.2023.04.003

Microneedling Options for Skin Rejuvenation, Including Non-temperature-controlled Fractional Microneedle Radiofrequency Treatments.

"Conventional microneedling and radiofrequency microneedling are considered safe and effective methods for skin rejuvenation ..."

"Treatments are safe for all skin types because, unlike lasers, they are chromophore blind."

"... 10 patients who underwent 6 microneedling treatments ... showed significant improvement in wrinkles, skin texture, and overall satisfaction as well as increased collagen and tropoelastin in biopsy specimens."

Videnskabelig reference

Alessa, D., & Bloom, J. D. (2020). Microneedling Options for Skin Rejuvenation, Including Non-temperature-controlled Fractional Microneedle Radiofrequency Treatments. Facial plastic surgery clinics of North America, 28(1), 1–7. https://doi.org/10.1016/j.fsc.2019.09.001

A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: a pilot study.

"Results: (1) Hair counts – The mean change in hair count at week 12 was significantly greater for the Microneedling group compared to the Minoxidil group (91.4 vs 22.2 respectively)."

Videnskabelig reference

Dhurat, R., Sukesh, M., Avhad, G., Dandale, A., Pal, A., & Pund, P. (2013). A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: a pilot study. International journal of trichology, 5(1), 6–11. https://doi.org/10.4103/0974-7753.114700

American Academy of Dermatology

Microneedling can fade scars, uneven skin tone, and more

"Microneedling is minimally invasive and safe for all skin tones. It works by stimulating your body to make collagen. This is why it’s also called “collagen induction therapy.”

https://www.aad.org/public/cosmetic/scars-stretch-marks/microneedling-fade-scars

Younger-looking skin

"Microneedling can treat signs of skin aging. Safe for all skin types, microneedling can diminish sagging skin, wrinkles, and fine lines."

https://www.aad.org/public/cosmetic/younger-looking

Yale Medicine

Microneedling

Though the thought of needles may make you cringe, microneedling is not painful. Doctors generally apply a topical anesthetic cream beforehand to help numb the area being treated...

https://www.yalemedicine.org/conditions/microneedling

Dermatology Times

Microneedling Produces Beneficial Acne Vulgaris Outcomes Without Disrupting Skin Structure or Microbiome

"In this pilot, microneedling did not cause post-treatment complications and was seen to reduce acne lesions effectively."

https://www.dermatologytimes.com/view/microneedling-produces-beneficial-acne-vulgaris-outcomes-without-disrupting-skin-structure-or-microbiome

The Journal of Clinical and Aesthetic Dermatology (JCAD)

A Comparison of Microneedling versus Glycolic Acid Chemical Peel for the Treatment of Acne Scarring

"Our study identifies microneedling as a better option than 35% glycolic acid chemical peels."

J Clin Aesthet Dermatol. 2022;15(6):48-52.

https://jcadonline.com/microneedling-acid-peel-acne-scarring/